HE small bowel metastasis of malignant melanoma

HE ovarian adenocarcinoma

HE human skin biopsy

HE lymph node metastasis of malignant melanoma

Giemsa Bone Marrow

HE Adenocarcinoma

Histopathology

Morphology at Your Finger Tips

Welcome to histopathology at HistoGeneX. We employ automated solutions, focus unwaveringly on standardization and maximize the information that can be obtained through the tissue specimens.

Morphological evaluation is foundational to analysis and decision-making and we fully leverage pathologist expertise with technology to harness the invaluable information contained in the specimens.

We provide the full suite of histopathology processes, almost all of it automated for reproducibility and standardization.

Furthermore, HistoGeneX pioneered the integration of digital pathology and image analysis in the industry. The laboratory has been capturing whole slide images in high-resolution format for 10 years and has developed an efficient workflow with numerous features to enhance your development processes.

  • Tissue Fixation & Processing
  • Paraffin Embedding & Sectioning (molecular included)
  • Frozen section embedding (OCT) and Cryostat Sectioning
  • Automated Hematoxylin and Eosin staining with Automated Special Stains
  • Digital Whole Slide Capture

Each slide is digitally captured in whole slide high-resolution format and retained in our image servers. The generation of these images is CAP and ISO 15189 accredited. 

  • Evaluation & Scoring

Evaluation and scoring is performed on high-resolution virtual images. 

Histopathology Report - Where It Starts

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At HistoGeneX the histopathology report drives all subsequent biomarker-related activity. A HistoGeneX board-certified pathologist generates the histopathology report. The report contains information (e.g. size, number of tumor cells, organization of microenvironment) about the tumor specimen and defines the tumor region. HistoGeneX technologists, scientist and imaging technicians then employ the report to determine whether the specimen is suitable for further analysis per sponsor criteria.

The histopathology report is used as a guiding map during image analysis, FISH, multi-analyte IHC and biomarker scoring.

The guiding map is also crucial during macrodissection for DNA-RNA extraction and for TMA design.